Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Diabetes and Dietary Supplements. Office of Dietary Supplements. Dietary Supplement Fact Sheet: Chromium. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes. J Clin Pharm Ther. A pilot study of chromium picolinate for weight loss. J Altern Complement Med. Your Privacy Rights. To change or withdraw your consent choices for VerywellHealth.
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Table of Contents. What Is Chromium Used For? Possible Side Effects. Dosage and Preparation. What to Look For. Adverse Effects of Chromium Picolinate. Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Related Articles. Adverse Effects of Taking Chromium Picolinate. What Is Chromium Polynicotinate? In: Vincent JB, ed. Chromium does not belong in the diabetes treatment arsenal: Current evidence and future perspectives. World J Diabetes ; Introduction: A history of chromium studies Cambridge, MA Elsevier; New evidence against chromium as an essential trace element. J Nutr ; Is the pharmacological mode of action of chromium III as a second messenger? Biol Trace Elem Res ; In: John W.
Erdman Jr. IAM, Steven H. Zeisel, ed. Present Knowledge in Nutrition. Nielsen FH. Summary: The metabolism, nutritional essentiality, and clinical importance of chromium -Clarity emerging after 60 years of research. Stability and absorption of chromium and absorption of chromium histidinate complexes by humans.
Bio Trace Elem Res ; Age-related decreases in chromium levels in 51, hair, sweat, and serum samples from 40, patients--implications for the prevention of cardiovascular disease and type II diabetes mellitus. Metabolism ; Chromium supplements in health and disease.
Dietary chromium intake. Freely chosen diets, institutional diet, and individual foods. Current concepts about chromium supplementation in type 2 diabetes and insulin resistance. Curr Diab Rep ; Chromium in Health and Disease. Nutr Today ; Chromium speciation in foodstuffs: A review. Food Chem ; Encyclopedia of Food and Health: Academic Press; Kuligowski J, Halperin KM. Stainless steel cookware as a significant source of nickel, chromium, and iron. Arch Environ Contam Toxicol ; Effects of diets high in simple sugars on urinary chromium losses.
Effects of antacid or ascorbic acid on tissue accumulation and urinary excretion of 51chromium. Nutr Res ; Food and Drug Administration. National Institutes of Health. Dietary Supplement Label Database. Komorowski J, Juturu V. Chromium supplementation does not improve glucose tolerance, insulin sensitivity, or lipid profile: a randomized, placebo-controlled, double-blind trial of supplementation in subjects with impaired glucose tolerance: response to Gunton et al.
Diabetes Care ;; author reply Department of Agriculture and Agricultural Research Service. What We Eat In America. Dietary intake of calcium, chromium, copper, iron, magnesium, manganese, and zinc: duplicate plate values corrected using derived nutrient intake. J Am Diet Assoc ; Dietary intake of cadmium, chromium, copper, manganese, selenium and zinc in a Northern Italy community.
J Trace Elem Med Biol ; Chromium deficiency after long-term total parenteral nutrition. Dig Dis Sci ; Chromium deficiency during total parenteral nutrition. JAMA ; Chromium deficiency, glucose intolerance, and neuropathy reversed by chromium supplementation, in a patient receiving long-term total parenteral nutrition. Am J Clin Nutr ; Trace elements in parenteral nutrition: a practical guide for dosage and monitoring for adult patients.
Nutr Clin Pract ; Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes ; Chromium supplements for glycemic control in type 2 diabetes: limited evidence of effectiveness.
Nutr Rev ; Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. Qualified Health Claims: Letters of Denial. Chromium picolinate intake and risk of type 2 diabetes: an evidence-based review by the United States Food and Drug Administration. Standards of medical care in diabetes Diabetes care ;33 Suppl 1:S Diabetes care ;38 Suppl:S Metabolic Syndrome.
Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults. Metab Syndr Relat Disord ; Sci Rep ; Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus. Endocr Pract Chromium supplementation reduces resting heart rate in patients with metabolic syndrome and impaired glucose tolerance.
Effects of zinc, magnesium, and chromium supplementation on cardiometabolic risk in adults with metabolic syndrome: A double-blind, placebo-controlled randomised trial. PCOS: update and diagnostic approach. Clin Biochem ; Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis. The possibilities of using chromium salts as an agent supporting treatment of polycystic ovary syndrome. Chromium supplementation in women with polycystic ovary syndrome: Systematic review and meta-analysis.
J Obstet Gynaecol Res ; The effects of supplementation with chromium on insulin resistance indices in women with polycystic ovarian syndrome: a systematic review and meta-analysis of randomized clinical trials. Horm Metab Res ; Chromium supplementation does not improve weight loss or metabolic and hormonal variables in patients with polycystic ovary syndrome: A systematic review.
Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. The influences of chromium supplementation on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome women candidate for in vitro fertilization: a randomized, double-blind, placebo-controlled trial.
Biol Trace Elem Res 1 : Chromium supplementation does not improve glucose tolerance, insulin sensitivity, or lipid profile: a randomized, placebo-controlled, double-blind trial of supplementation in subjects with impaired glucose tolerance. Diabetes Care ; Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials.
A meta-analysis on the effect of chromium picolinate on glucose and lipid profiles among patients with type 2 diabetes mellitus. Philipp J Intern Med ; Effect of chromium on glucose and lipid profiles in patients with type 2 diabetes; a meta-analysis review of randomized trials.
J Pharm Pharm Sci ; Always tell your doctor if you are using a dietary supplement or if you are thinking about combining a dietary supplement with your conventional medical treatment. It may not be safe to forgo your conventional medical treatment and rely only on a dietary supplement. This is especially important for women who are pregnant or breastfeeding.
Author: Healthwise Staff. This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information.
Your use of this information means that you agree to the Terms of Use. Learn how we develop our content. To learn more about Healthwise, visit Healthwise. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. Updated visitor guidelines. You are here Home » Chromium. Top of the page. Topic Overview What is chromium? What is chromium used for? Chromium may help some people with type 2 diabetes. It may help them control their blood sugar and may play a role in the management of type 2 diabetes.
But more studies are needed to know how well it really works.
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